Dina M. Sigano: search on Z-Library

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1

Carbene−Alkyne−Alkene Cyclization Reactions

Harvey, Daniel F., Sigano, Dina M.

Journal:

Chemical Reviews

Year:

1996

Language:

english

File:

PDF, 1.65 MB

english, 1996

2

Conformationally Constrained Analogues of Diacylglycerol (DAG). 23 † . Hydrophobic Ligand−Protein Interactions versus Ligand−Lipid Interactions of DAG-Lactones with Protein Kinase C (PK-C)

Tamamura, Hirokazu, Sigano, Dina M., Lewin, Nancy E., Peach, Megan L., Nicklaus, Marc C., Blumberg, Peter M., Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 189 KB

english, 2004

3

Conformationally Constrained Analogues of Diacylglycerol. 29. Cells Sort Diacylglycerol-Lactone Chemical Zip Codes to Produce Diverse and Selective Biological Activities

Duan, Dehui, Sigano, Dina M., Kelley, James A., Lai, Christopher C., Lewin, Nancy E., Kedei, Noemi, Peach, Megan L., Lee, Jeewoo, Abeyweera, Thushara P., Rotenberg, Susan A., Kim, Hee, Kim, Young Ho,

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 3.49 MB

english, 2008

4

Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities

Or Raifman, Dr. Sofiya Kolusheva, Dr. Said El Kazzouli, Dr. Dina M. Sigano, Dr. Noemi Kedei, Dr. Nancy E. Lewin, Ruben Lopez-Nicolas, Ana Ortiz-Espin, Juan C. Gomez-Fernandez, Dr. Peter M. Blumberg, D

Journal:

Year:

2010

Language:

english

File:

PDF, 488 KB

english, 2010

5

North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity

Pamela L. Russ, Maria J. Gonzalez-Moa, B. Christie Vu, Dina M. Sigano, James A. Kelley, Christopher C. Lai, Jeffrey R. Deschamps, Stephen H. Hughes, Victor E. Marquez

Journal:

Year:

2009

Language:

english

File:

PDF, 363 KB

english, 2009

6

Conformationally Constrained Analogues of Diacylglycerol (DAG). 27. Modulation of Membrane Translocation of Protein Kinase C (PKC) Isozymes α and δ by Diacylglycerol Lactones (DAG- l actones) Containing Rigid-Rod Acyl Groups

Malolanarasimhan, Krishnan, Kedei, Noemi, Sigano, Dina M., Kelley, James A., Lai, Christopher C., Lewin, Nancy E., Surawski, Robert J., Pavlyukovets, Vladimir A., Garfield, Susan H., Wincovitch, Steph

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 521 KB

english, 2007

7

Conformationally Constrained Analogues of Diacylglycerol. 20. The Search for an Elusive Binding Site on Protein Kinase C through Relocation of the Carbonyl Pharmacophore Along the sn -1 Side Chain of 1,2-Diacylglycerol Lactones

Tamamura, Hirokazu, Sigano, Dina M., Lewin, Nancy E., Blumberg, Peter M., Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 209 KB

english, 2004

8

Conformationally Constrained Analogues of Diacylglycerol. 26. Exploring the Chemical Space Surrounding the C1 Domain of Protein Kinase C with DAG-Lactones Containing Aryl Groups at the sn -1 and sn -2 Positions

Kang, Ji-Hye, Benzaria, Samira, Sigano, Dina M., Lewin, Nancy E., Pu, Yongmei, Peach, Megan L., Blumberg, Peter M., Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 358 KB

english, 2006

9

Conformationally Constrained Analogues of Diacylglycerol (DAG). 28. DAG-dioxolanones Reveal a New Additional Interaction Site in the C1b Domain of PKCδ

Choi, Yongseok, Pu, Yongmei, Peach, Megan L., Kang, Ji-Hye, Lewin, Nancy E., Sigano, Dina M., Garfield, Susan H., Blumberg, Peter M., Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 814 KB

english, 2007

10

Diacylglycerol Lactones Targeting the Structural Features That Distinguish the Atypical C1 Domains of Protein Kinase C ζ and ι from Typical C1 Domains

Pu, Yongmei, Kang, Ji-Hye, Sigano, Dina M., Peach, Megan L., Lewin, Nancy E., Marquez, Victor E., Blumberg, Peter M.

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

11

Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain

Strope, Jonathan D., Peer, Cody J., Sissung, Tristan M., Hall, O. Morgan, Huang, Phoebe A., Harris, Emily M., Gustafson, Kirk R., Henrich, Curtis J., Sigano, Dina M., Pauly, Gary T., Schneider, Joel P

Journal:

Cancer Biology & Therapy

Year:

2019

Language:

english

File:

PDF, 1.96 MB

english, 2019

12

Inside Cover: Membrane-Surface Anchoring of Charged Diacylglycerol-Lactones Correlates with Biological Activities (ChemBioChem 14/2010)

Or Raifman, Dr. Sofiya Kolusheva, Dr. Said El Kazzouli, Dr. Dina M. Sigano, Dr. Noemi Kedei, Dr. Nancy E. Lewin, Ruben Lopez-Nicolas, Ana Ortiz-Espin, Juan C. Gomez-Fernandez, Dr. Peter M. Blumberg, D

Journal:

Year:

2010

File:

PDF, 618 KB

2010

13

Inside Cover: North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity (ChemMedChem 8/2009)

Pamela L. Russ, Maria J. Gonzalez-Moa, B. Christie Vu, Dina M. Sigano, James A. Kelley, Christopher C. Lai, Jeffrey R. Deschamps, Stephen H. Hughes, Victor E. Marquez

Journal:

Year:

2009

Language:

english

File:

PDF, 471 KB

english, 2009

14

Materials from peptide assembly: towards the treatment of cancer and transmittable disease

Monica C Branco, Dina M Sigano, Joel P Schneider

Journal:

Current Opinion in Chemical Biology

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

15

Alkyl Amine Bevirimat Derivatives are Potent and Broadly Active HIV-1 Maturation Inhibitors

Urano, Emiko, Ablan, Sherimay D., Mandt, Rebecca, Pauly, Gary T., Sigano, Dina M., Schneider, Joel P., Martin, David E., Nitz, Theodore J., Wild, Carl T., Freed, Eric O.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 1.25 MB

english, 2015

16

Infectious Entry and Neutralization of Pathogenic JC Polyomaviruses

Geoghegan, Eileen M., Pastrana, Diana V., Schowalter, Rachel M., Ray, Upasana, Gao, Wei, Ho, Mitchell, Pauly, Gary T., Sigano, Dina M., Kaynor, Campbell, Cahir-McFarland, Ellen, Combaluzier, Benoit, G

Journal:

Year:

2017

Language:

english

File:

PDF, 2.57 MB

english, 2017

17

Synthesis of Cyclopropylpyrrolidines via Reaction of N -Allyl- N -propargylamides with a Molybdenum Carbene Complex. Effect of Substituents and Reaction Conditions

Harvey, Daniel F., Sigano, Dina M.

Journal:

Journal of Organic Chemistry

Year:

1996

Language:

english

File:

PDF, 235 KB

english, 1996

18

N-Methyl-Substituted Fluorescent DAG–Indololactone Isomers Exhibit Dramatic Differences in Membrane Interactions and Biological Activity

Noga Gal, Dr. Sofiya Kolusheva, Dr. Noemi Kedei, Dr. Andrea Telek, Taiyabah A. Naeem, Nancy E. Lewin, Langston Lim, Poonam Mannan, Susan H. Garfield, Dr. Saïd El Kazzouli, Dr. Dina M. Sigano, Dr. Vict

Journal:

Year:

2011

Language:

english

File:

PDF, 6.65 MB

english, 2011

19

Ceramides: Branched alkyl chains in the sphingolipid siblings of diacylglycerol improve biological potency

Ji-Hye Kang, Himanshu Garg, Dina M. Sigano, Nicholas Francella, Robert Blumenthal, Victor E. Marquez

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 816 KB

english, 2009

20

Conformationally Constrained Analogues of Diacylglycerol. 21. A Solid-Phase Method of Synthesis of Diacylglycerol Lactones as a Prelude to a Combinatorial Approach for the Synthesis of Protein Kinase C Isozyme-Specific Ligands

Duan, Dehui, Lewin, Nancy E., Sigano, Dina M., Blumberg, Peter M., Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 94 KB

english, 2004

21

Conformationally Constrained Analogues of Diacylglycerol. 24. Asymmetric Synthesis of a Chiral ( R )-DAG-Lactone Template as a Versatile Precursor for Highly Functionalized DAG-Lactones

Kang, Ji-Hye, Siddiqui, Maqbool A., Sigano, Dina M., Krajewski, Krzysztof, Lewin, Nancy E., Pu, Yongmei, Blumberg, Peter M., Lee, Jeewoo, Marquez, Victor E.

Journal:

Organic Letters

Year:

2004

Language:

english

File:

PDF, 74 KB

english, 2004

22

An Optimized Protein Kinase C Activating Diacylglycerol Combining High Binding Affinity ( K i ) with Reduced Lipophilicity (log P)

Nacro, Kassoum, Sigano, Dina M., Yan, Shunqi, Nicklaus, Marc C., Pearce, Larry L., Lewin, Nancy E., Garfield, Susan H., Blumberg, Peter M., Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 332 KB

english, 2001

23

Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain

Strope, Jonathan D., Peer, Cody J., Sissung, Tristan M., Hall, O. Morgan, Huang, Phoebe A., Harris, Emily M., Gustafson, Kirk R., Henrich, Curtis J., Sigano, Dina M., Pauly, Gary T., Schneider, Joel P

Journal:

Cancer Biology & Therapy

Year:

2019

File:

PDF, 1.96 MB

2019

24

Differential Binding Modes of Diacylglycerol (DAG) and DAG Lactones to Protein Kinase C (PK-C)

Sigano, Dina M., Peach, Megan L., Nacro, Kassoum, Choi, Yongseok, Lewin, Nancy E., Nicklaus, Marc C., Blumberg, Peter M., Marquez, Victor E.

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 420 KB

english, 2003

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